解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVES:To assess the association between prenatal exposure to monotherapy with the antiepileptic drugs (AEDs) most commonly used during pregnancy and the risk of various neurodevelopmental outcomes compared with lamotrigine. DESIGN:Nationwide population-based cohort study. SETTING:French national healthcare datab...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034829
更新日期:2020-06-07 00:00:00
abstract:OBJECTIVES:This study investigated self-perception of overall health (SPH) and quality of life (QoL) at onset and after 3, 6 and 12 months of fitness club membership. Also, we compared SPH and QoL between those who reported regular use of the fitness club (≥2 exercise sessions/week the last month) with those who did no...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036250
更新日期:2020-06-07 00:00:00
abstract:INTRODUCTION:Recent evidence has implicated the precuneus of the medial parietal lobe as one of the first brain areas to show pathological changes in Alzheimer's disease (AD). Damage to the precuneus through focal brain injury is associated with impaired visually guided reaching, particularly for objects in peripheral ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035021
更新日期:2020-06-04 00:00:00
abstract:OBJECTIVES:The prevalence of neck/back pain (NBP) is high worldwide. Limited number of studies have investigated workers with occasional NBP regarding the risk of developing long-duration activity limiting NBP (LNBP). The objectives were to assess (1) the effect of poor work ability and sleep disturbances in persons wi...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033946
更新日期:2020-06-03 00:00:00
abstract:OBJECTIVE:To explore experts' views on factors influencing national and global active case-finding (ACF) policy development and implementation, and the use of evidence in these processes. DESIGN:This is an exploratory study based on semistructured expert interviews. Framework analysis was applied. PARTICIPANTS:The st...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036285
更新日期:2020-06-03 00:00:00
abstract:OBJECTIVES:To assess variation in antibiotic prescribing practices among village doctors in a rural region of Shandong province, China. DESIGN, SETTING AND PARTICIPANTS:Almost all outpatient encounters at village clinics result in a prescription being issued. Prescriptions were collected over a 2.5-year period from 8 ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036703
更新日期:2020-06-01 00:00:00
abstract:INTRODUCTION:Over 5 billion people in the world do not have access to safe, affordable surgical and anaesthesia care when needed. In order to improve health outcomes in patients with surgical conditions, both access to care and the quality of care need to be improved. A recent commission on high-quality health systems ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036615
更新日期:2020-05-30 00:00:00
abstract:OBJECTIVE:To examine the effects of a consultant-led, community-based chronic obstructive pulmonary disease (COPD) service, based in a highly deprived area on emergency hospital admissions. DESIGN:A longitudinal matched controlled study using difference-in-differences analysis to compare the change in outcomes in the ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032931
更新日期:2020-05-27 00:00:00
abstract:PURPOSE:Depression is the most common psychiatric disorder and the largest contributor to global disability. The Australian Genetics of Depression study was established to recruit a large cohort of individuals who have been diagnosed with depression at some point in their lifetime. The purpose of establishing this coho...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032580
更新日期:2020-05-26 00:00:00
abstract:OBJECTIVE:To investigate social inequalities underlying low birthweight (LBW) outcomes in Sri Lanka. DESIGN:Cross-sectional study. SETTING:This study used the Sri Lanka Demographic and Health Survey 2016, the first such survey to cover the entire country since the Civil War ended in 2001. PARTICIPANTS:Birthweight da...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-037223
更新日期:2020-05-25 00:00:00
abstract:INTRODUCTION:Streptococcus pneumoniae and non-typeable Haemophilus influenzae (NTHi) are major otitis media pathogens that densely co-colonise the nasopharynx and infect the middle ear of Australian Aboriginal infants from very early in life. Our co-primary hypotheses are that at 18 months of age infants receiving 10-v...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033511
更新日期:2020-05-24 00:00:00
abstract:OBJECTIVES:The present study aimed to assess the level of knowledge on peripherally inserted central catheter (PICC) maintenance among nurses in China and to analyse the related factors influencing this variable. DESIGN:A cross-sectional survey. SETTING:Ninety-one hospitals at three different levels in Hunan Province...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033804
更新日期:2020-05-21 00:00:00
abstract:INTRODUCTION:Insomnia is a highly prevalent and costly condition that is associated with increased health risks and healthcare utilisation. Anecdotally, cannabis use is frequently reported by consumers to promote sleep. However, there is limited research on the effects of cannabis on sleep and daytime function in peopl...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034421
更新日期:2020-05-18 00:00:00
abstract:INTRODUCTION:Reduction in low-density lipoprotein cholesterol (LDL-C) improves clinical outcomes in patients with coronary artery disease. However, rates of lipid-lowering medication adherence are far from ideal. Reducing dosage frequency from multiple dosing to once-daily dosing may improve patients' medication adhere...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034585
更新日期:2020-05-17 00:00:00
abstract:OBJECTIVES:To investigate mortality in adults with intellectual disabilities: rates, causes, place, demographic and clinical predictors. DESIGN:Cohort study with record linkage to death data. SETTING:General community. PARTICIPANTS:961/1023 (94%) adults (16-83 years; mean=44.1 years; 54.6% male) with intellectual di...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036465
更新日期:2020-05-17 00:00:00
abstract:OBJECTIVES:To explore the social and academic experiences of nursing transfer students' (NTSs) in an Asian context. DESIGN:A descriptive qualitative study design using focus groups and individual interviews with Chinese NTSs. The data were transcribed verbatim and analysed by using qualitative content analysis. SETTI...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034205
更新日期:2020-05-15 00:00:00
abstract:INTRODUCTION:Up to 1 in 4 pregnancies and 1 in 20 subsequent pregnancies end in miscarriage. Despite such prevalence the psychosocial effects are often unrecognised and unsupported. In the absence of any biomedical sequelae among men such marginalisation may be intensified. Men living through multiple miscarriages may ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035967
更新日期:2020-05-15 00:00:00
abstract:INTRODUCTION:Adolescence and young adulthood is a period in life when individuals may be especially vulnerable to harmful substance use. Several critical developmental processes are occurring in the brain, and substance use poses both short-term and long-term risks with regard to mental health and social development. F...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034894
更新日期:2020-05-12 00:00:00
abstract:INTRODUCTION:In Australia, suicide is the leading cause of death for people aged 15-44 years. Health professionals deliver most of our key suicide prevention strategies via health services, but other efficacious population-level strategies include means restriction and public awareness campaigns. Currently, we have no ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-038181
更新日期:2020-05-11 00:00:00
abstract:OBJECTIVES:Two oral targeted therapies, gefitinib and erlotinib, were first approved and then launched into the market for treatment of late-stage non-small cell lung cancer (NSCLC) in Taiwan in 2003 and 2006, respectively. The aim of this study were to determine the trends in lung cancer burden and examine changes in ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033427
更新日期:2020-05-10 00:00:00
abstract:INTRODUCTION:Depression is a common mental disorder in the elderly population, which significantly impacts their quality of life. However, correct estimates of its magnitude are not available in the elderly in India. The present systematic review and meta-analysis would attempt to estimate the prevalence of depression ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034330
更新日期:2020-05-07 00:00:00
abstract:OBJECTIVES:A Demographic and Health Platform was established in Magude in 2015, prior to the deployment of a project aiming to evaluate the feasibility of malaria elimination in southern Mozambique, named the Magude project. This platform aimed to inform the design, implementation and evaluation of the Magude project, ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033985
更新日期:2020-05-05 00:00:00
abstract:OBJECTIVES:National guidelines for identifying physiological deterioration and sepsis in hospitals depend on thresholds for blood pressure that do not account for age or sex. In populations outside hospital, differences in blood pressure are known to occur with both variables. Whether these differences remain in the ho...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033618
更新日期:2020-05-05 00:00:00
abstract:INTRODUCTION:Healthcare systems around the world are looking for solutions to the growing problem of mental disorders. RECOVER is the synonym for an evidence-based, stepped and cross-sectoral coordinated care service model for mental disorders. RECOVER implements a cross-sectoral network with managed care, comprehensiv...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036021
更新日期:2020-05-04 00:00:00
abstract:INTRODUCTION:Delirium is frequently observed in the intensive care unit (ICU) population, in particular. Until today, there is no evidence for any reliable pharmacological intervention to treat delirium. The Basel BOMP-AID (Better Outcome with Melatonin compared to Placebo Administered to normalize sleep-wake cycle and...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034873
更新日期:2020-04-30 00:00:00
abstract:OBJECTIVES:This study aimed to identify intrauterine growth differences according to infertility treatment compared with spontaneous conception and to describe intrauterine growth trajectories. DESIGN:Retrospective cohort study. SETTING:A single primary and tertiary medical centre in Japan. PARTICIPANTS:This study i...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033675
更新日期:2020-04-28 00:00:00
abstract:INTRODUCTION:Drug-related problems (DRPs) are a major cause of unplanned hospital admissions among elderly people, and transitions of care have been emphasised as a key area for improving patient safety. We have designed a complex clinical pharmacist intervention that targets people ≥75 years of age undergoing transiti...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036650
更新日期:2020-04-27 00:00:00
abstract:INTRODUCTION:Internet-based and mobile-based interventions (IMIs) provide an innovative and efficient self-management tool for mental health problems. This systematic review aims to summarise and critically evaluate studies addressing the effectiveness and feasibility of IMIs for normal and complicated grief in bereave...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036034
更新日期:2020-04-22 00:00:00
abstract:OBJECTIVE:Making the diagnosis of asthma is challenging. Guidelines recommend that clinicians identify a group at 'high probability' of asthma. High probability, however, is not numerically defined giving rise to uncertainty. The aim of this work was to build consensus on what constitutes a high probability of asthma i...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034559
更新日期:2020-04-20 00:00:00
abstract:OBJECTIVE:The purpose of this study was to analyse the rate of knee arthroplasty in the population of patients with a history of arthroscopic chondroplasty of the knee, in England, over 10 years, with comparison to general population data for patients without a history of chondroplasty. DESIGN:Retrospective cohort stu...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-030609
更新日期:2020-04-16 00:00:00
abstract:OBJECTIVE:To quantify general practitioners' (GPs) sensitivity to anxiety disorders (ADs) when confronted with the range of symptoms common to children with ADs. Also, to explore GPs' conscious preferences and implicit tendencies for referral of children with ADs to mental healthcare. DESIGN AND SETTING:In a cross-sec...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035799
更新日期:2020-04-15 00:00:00
abstract:INTRODUCTION:Adolescence is a critical period for youths with chronic conditions, when they are supposed to take over the responsibility for their health. Type 1 diabetes (T1D) is one of the most common chronic conditions in childhood and inadequate self-management increases the risk of short-term and long-term complic...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036496
更新日期:2020-04-14 00:00:00
abstract:OBJECTIVES:To analyse the completeness of reporting of blinding in randomised controlled trials (RCTs) of interventions in anaesthesiology, the actual blinding status of various persons associated with an RCT and trial authors' interpretation of blinding terminology related to RCTs. METHODS:This was a methodological s...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035168
更新日期:2020-04-12 00:00:00
abstract:INTRODUCTION:Though the importance of knowledge mobilisation has been established globally in health and wellness research, a certain degree of ambiguity remains regarding the meaning and extent of knowledge mobilisation activities and how they have been implemented. In this study, we aim to explore the different descr...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036081
更新日期:2020-04-08 00:00:00
abstract:INTRODUCTION:Acute kidney injury (AKI) is a frequent complication after cardiac surgery with adverse short-term and long-term outcomes. Although prevention of AKI (PrevAKI) is strongly recommended, the optimal strategy is uncertain. The Kidney Disease: Improving Global Outcomes (KDIGO) guideline recommended a bundle of...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034201
更新日期:2020-04-06 00:00:00
abstract:OBJECTIVE:Leadership is associated with organisational performance in healthcare, including quality, safety and clinical outcomes for patients. Leadership development programmes have proliferated in recent years. Nevertheless, very few have examined participant experiences in depth in order to understand which programm...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035797
更新日期:2020-04-06 00:00:00
abstract:OBJECTIVES:To compare days on sick leave and assess predictors of return to work following shoulder surgery. DESIGN:A secondary analysis of a randomised controlled trial. SETTING:Orthopaedic department. PARTICIPANTS:114 patients with type II superior labral tear from anterior to posterior of the shoulder. INTERVENT...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035259
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVES:Liver disease is a major cause of morbidity and mortality in sub-Saharan Africa, but its prevalence, distribution and aetiology have not been well characterised. We therefore set out to examine liver function tests (LFTs) and liver fibrosis scores in a rural African population. DESIGN:We undertook a cross-s...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032890
更新日期:2020-03-31 00:00:00
abstract:INTRODUCTION:Although shortcomings in clinician-family communication and decision making for incapacitated, critically ill patients are common, there are few rigorously tested interventions to improve outcomes. In this manuscript, we present our methodology for the Pairing Re-engineered Intensive Care Unit Teams with N...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033521
更新日期:2020-03-29 00:00:00
abstract:OBJECTIVE:In 2001, Chinese guidelines for the care of acute myocardial infarction (AMI) included a new recommendation against the routine use of magnesium. We studied temporal trends and institutional variation in the use of intravenous magnesium sulfate in nationally representative samples of individuals hospitalised ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033269
更新日期:2020-03-26 00:00:00